The OPA/Alum foil is made of a thin Aluminium layer laminated with OPA (oriented polyamide known as nylon). The laminate is especially suitable for drugs that are easily affected even when other units in the pack are opened. This foil uses the packaging of pharmaceutical finished products like, tablets, capsules, and other forms.
1.Description:
The aluminium foil is laminated with OPA (oriented polyamide). One side is printed, the other is plain, or both are plain unprinted foil.
2. Text matter:
The OPA/Alum Foil is printed, and the foil is printed text matter to match a shade card or artwork.
3. Color scheme:
The foil OPA/Alum sample is a printed text matter color scheme that matches with a shade card or Pantone card.
4. Width:
The sample OPA/Alum foil measures the width of the foil with the help of a measuring scale. The selected sample measures the sample and notes the reading.
5. Inner core Diameter:
The sample OPA/Alum foil is in a roll form and the sample inner core diameter is measured with the help of a measuring scale. Take the sample reading and note it down
- Grammage:
- Total Grammage:
The sample of OPA/Alum foil is the total Grammage testing, the sample is cut 10 x 10 cm or 5 x 5 cm (if applicable) with the help of a GSM plate. Weighing the sample at analytical balance, calculate the Grammage by the given formula,
Total Grammage= weight in grams x 100 or 400 (if the sample cut 10 x 10 or 5 x 5 cm)
- FOR OPA Layer:
Take the total Grammage sample and dip the sample glass beaker containing the 10% solution of sodium hydroxide solution. After some time the aluminium layer is dissolved in this solution. The remaining sample is the OPA layer. Dry the sample in a hot air oven for 1 minute at 700c. Weighing the OPA layer at analytical balance, then calculate the Grammage by the given formula,
OPA Layer Grammage = weight in grams x 100 or 400 (if the sample cut 10 x 10 or 5 x 5 cm)
- For the Aluminium layer
Grammage of Aluminium layer = Total Grammage – OPA Layer Grammage
7. Identification of the Aluminium layer:
The sample of OPA/Alum foil is For the identification testing of the aluminium Layer, Weigh the sample of the 15 mg sample and put it in a beaker mixing 30ml 1NHCL then heat the beaker aluminium foil to dissolve, in solution add about 1 ml HCL and 1 ml of thioacetamide regents, no precipitate is formed, add dropwise NaoH solution, a gelatinous white precipitate is formed which dissolve on further addition of 1NaoH Solution after gradually addition ammonium hydroxide solution .gelatinous white precipitate is re-formed.
8. Thickness of the OPA/Alum foil:
- Total Thickness:
The selected sample of OPA/Alum foil is tested for total thickness measuring with the help of a digital micrometer, the sample measures the reading and notes the measured reading.
- For OPA Layer:
The selected sample of OPA layer Grammage sample is tested for total thickness measuring with the help of a digital micrometer, the sample measures the reading and notes the measured reading.
9. Pinhole testing of OPA/Alum foil
The sample of OPA/Alum foil testing of pinhole, Take the OPA/Alum Foil test performed by Illuminated magnifier tester instrument. Its instruments are in the background white light. On the instrument put the sample on the front of the bench. We neck eye verify the sample. When the observed sample has any hole the light is passed from the hole. It is easy to identify and ensure the sample has no pine holes.
I am Maneesh Maurya a professional pharmaceutical blogger from India having rich experience in the pharmaceutical Quality control field.
