Regent
- Copper Sulphate pentahydrate (Cuso4.5H2O)
- Acetic acid 100 pa (HAc)
- Wetting agent
Or
Electrolyte-mixed copper sulphate solution containing copper sulphate acetic acid and wetting agent
Procedure
- Set the instrument per the user manuals and follow test parameters for the copper sulphate method of lacquer test as mentioned in the table below.
parameter | procedure |
Electrodes porosity | The dipping electrode is the position pole |
material | Dipping electrode copper (plastic cap has to be mounted on the bottom of the electrode to avoid direct contact between electrode and tube shoulder adapter electrode stainless steel) |
2) Preparation of electrolyte
- Dissolve 10 g of Cuso4. 5H2O in deionized water, add the HAc and wetting agent and make it 1000 ml ± 2 ml with deionized water.
- The electrolyte conductivity of the finish solution shall be (4.75 ± 0.25)mS
OR
Readymade solution of electrolyte (mixed copper solution, acetic acid and wetting agent) can be used for analysis
- The tube to be tested is filled with the electrolyte up to 10 mm from the end and the tube is held in the stainless steel jaw on the apparatus
- A dipping electrode is inserted centrally into the tube, avoiding any contact between the tube wall/tube shoulder
- Start the measurement- application of voltage immediately
- The reading as displayed on the instrument is noted in mA after the measuring interval
- The limit for the same is as mentioned below.
Tube diameter (mm) | Single value (mA) |
Between 0 to 28 (mm) | Less than equal to 80 |
Between 28 to 45 (mm) | Less than equal to 80 |
Between 45 to 50 (mm) | Less than equal to 80 |
I am Maneesh Maurya a professional pharmaceutical blogger from India having rich experience in the pharmaceutical Quality control field.
